Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease

Michael W. Beck; Michael W. Beck; Jeffrey S. Derrick; Richard A. Kerr; Shin Bi Oh; Woo Jong Cho; Shin Jung C. Lee; Yonghwan Ji; Jiyeon Han; Zahra Aliakbar Tehrani; Nayoung Suh; Sujeong Kim; Scott D. Larsen; Kwang S. Kim; Joo Yong Lee; Brandon T. Ruotolo; Mi Hee Lim

doi:10.1038/ncomms13115

Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease

Michael W. Beck
, Michael W. Beck
, Jeffrey S. Derrick
, Richard A. Kerr
, Shin Bi Oh
, Woo Jong Cho
, Shin Jung C. Lee
, Yonghwan Ji
, Jiyeon Han
, Zahra Aliakbar Tehrani
, Nayoung Suh
, Sujeong Kim
, Scott D. Larsen
, Kwang S. Kim
, Joo Yong Lee
, Brandon T. Ruotolo
, Mi Hee Lim

School of Technology

University of Michigan
Ulsan National Institute of Science and Technology
University of Ulsan
Medicinal Chemistry

Research output: Contribution to journal › Article › peer-review

Original language	American English
Journal	Nature Communications
Volume	7
DOIs	https://doi.org/10.1038/ncomms13115
State	Published - Dec 1 2016

Disciplines

Biology
Genetics
Toxicology
Cell Biology

Access to Document

10.1038/ncomms13115License: Unspecified

Cite this

Beck, M. W., Beck, M. W., Derrick, J. S., Kerr, R. A., Oh, S. B., Cho, W. J., Lee, S. J. C., Ji, Y., Han, J., Tehrani, Z. A., Suh, N., Kim, S., Larsen, S. D., Kim, K. S., Lee, J. Y., Ruotolo, B. T., & Lim, M. H. (2016). Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease. Nature Communications, 7. https://doi.org/10.1038/ncomms13115

@article{ba833986f44d4e19ae27dbe38af9f51b,

title = "Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer{\textquoteright}s disease",

author = "Beck, \{Michael W.\} and Beck, \{Michael W.\} and Derrick, \{Jeffrey S.\} and Kerr, \{Richard A.\} and Oh, \{Shin Bi\} and Cho, \{Woo Jong\} and Lee, \{Shin Jung C.\} and Yonghwan Ji and Jiyeon Han and Tehrani, \{Zahra Aliakbar\} and Nayoung Suh and Sujeong Kim and Larsen, \{Scott D.\} and Kim, \{Kwang S.\} and Lee, \{Joo Yong\} and Ruotolo, \{Brandon T.\} and Lim, \{Mi Hee\}",

year = "2016",

month = dec,

day = "1",

doi = "10.1038/ncomms13115",

language = "American English",

volume = "7",

journal = "Nature Communications",

issn = "2041-1723",

}

TY - JOUR

T1 - Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease

AU - Beck, Michael W.

AU - Derrick, Jeffrey S.

AU - Kerr, Richard A.

AU - Oh, Shin Bi

AU - Cho, Woo Jong

AU - Lee, Shin Jung C.

AU - Ji, Yonghwan

AU - Han, Jiyeon

AU - Tehrani, Zahra Aliakbar

AU - Suh, Nayoung

AU - Kim, Sujeong

AU - Larsen, Scott D.

AU - Kim, Kwang S.

AU - Lee, Joo Yong

AU - Ruotolo, Brandon T.

AU - Lim, Mi Hee

PY - 2016/12/1

Y1 - 2016/12/1

UR - http://scholarworks.unist.ac.kr/bitstream/201301/20599/1/Lim-2016-NatCommun.pdf

U2 - 10.1038/ncomms13115

DO - 10.1038/ncomms13115

M3 - Article

SN - 2041-1723

VL - 7

JO - Nature Communications

JF - Nature Communications

ER -

Structure-mechanism-based engineering of chemical regulators targeting distinct pathological factors in Alzheimer’s disease

Disciplines

Access to Document

Other files and links

Cite this