@article{da9343f137754604bfa32c89be22bb18,
title = "Direct selection of hepatoma cell variants deficient in α1-antitrypsin gene expression",
author = "Bulla, \{Gary A.\} and Fournier, \{R. E. K.\}",
note = "Expression plasmids containing the human α 1-antitrypsin (α 1 AT) promoter fused to either adenine phosphoribosyltransferase (aprt) or xanthine-guanine phosphoribosyltransferase (gpt) coding sequences were sequentially introduced into APRT − HPRT − rat hepatoma cells. Stable transfectants expressing both transgenes were isolated and characterized. Nonexpressing variants were subsequently obtained by selecting against expression of one or both transgenes.",
year = "1992",
month = jul,
day = "1",
doi = "10.1007/BF01235759",
language = "American English",
volume = "18",
journal = "Somatic Cell and Molecular Genetics",
}