Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation

Krysten A Jones; Kaitlin Kentala; Michael W Beck; Weiwei An; Alexander Lippert; Jared C Lewis; Bryan C. Dickinson

doi:10.26434/chemrxiv.8258633.v1

Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation

Krysten A Jones
, Kaitlin Kentala
, Michael W Beck
, Weiwei An
, Alexander Lippert
, Jared C Lewis
, Bryan C. Dickinson

Eastern Illinois University

University of Chicago
Southern Methodist University
Indiana University - Bloomington

Research output: Working paper › Preprint

Original language	American English
DOIs	https://doi.org/10.26434/chemrxiv.8258633.v1
State	Published - Jun 2019

Disciplines

Life Sciences
Biochemistry, Biophysics, and Structural Biology
Biology
Chemistry

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Cite this

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title = "Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation",

author = "Jones, \{Krysten A\} and Kaitlin Kentala and Beck, \{Michael W\} and Weiwei An and Alexander Lippert and Lewis, \{Jared C\} and Dickinson, \{Bryan C.\}",

note = "Split reporters based on fluorescent proteins and luciferases have emerged as valuable tools for measuring interactions in biological systems. Relatedly, biosensors that transduce measured input signals into outputs that influence the host system are key components of engineered gene circuits for synthetic biology applications.",

year = "2019",

month = jun,

doi = "10.26434/chemrxiv.8258633.v1",

language = "American English",

type = "WorkingPaper",

}

TY - UNPB

T1 - Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation

AU - Jones, Krysten A

AU - Kentala, Kaitlin

AU - Beck, Michael W

AU - An, Weiwei

AU - Lippert, Alexander

AU - Lewis, Jared C

AU - Dickinson, Bryan C.

N1 - Split reporters based on fluorescent proteins and luciferases have emerged as valuable tools for measuring interactions in biological systems. Relatedly, biosensors that transduce measured input signals into outputs that influence the host system are key components of engineered gene circuits for synthetic biology applications.

PY - 2019/6

Y1 - 2019/6

UR - https://chemrxiv.org/articles/Development_of_a_Split_Esterase_1_for_Protein-Protein_2_Interaction_Dependent_Small_Molecule_Activation/8258633

U2 - 10.26434/chemrxiv.8258633.v1

DO - 10.26434/chemrxiv.8258633.v1

M3 - Preprint

BT - Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation

ER -

Development of a Split Esterase for Protein-Protein Interaction Dependent Small Molecule Activation

Disciplines

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